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Infradian Rhythm in Proliferative Activity of a Culture of Embryonic Fibroblast-Like Cells from C57BL/6 Mice

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We studied daily dynamics of proliferative activity of embryonic fibroblast-like cells in culture during the logarithmic growth phase. Daily increase in cell count in the culture showed a 4-day rhythm that persisted over 3 weeks of culturing. In cultures from different animals, the phase of this rhythm was synchronous and did not depend on the moment of cell isolation. It can be hypothesized that the 4-day biorhythm of proliferative activity of embryonic fibroblast-like cells in culture is determined by external environmental factors, probably of electromagnetic nature.

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References

  1. Belidheva NK, Popov AN. The dynamics of the morphological and functional state of cell cultures with variations of the geomagnetic field at high latitudes. Biofizika. 1995;40(4):755-764. Russian.

    Google Scholar 

  2. Diatroptov MЕ, Diatroptova MA. Infradian Biorhythm of Thyroid Hormone Concentrations in Mammals and Birds. Bull. Exp. Biol. Med. 2017;162(6):815-819. doi: https://doi.org/10.1007/s10517-017-3720-3

    Article  CAS  Google Scholar 

  3. Diatroptov ME, Makarova OV. Infradian Biorhythms of Mitotic Activity Esophageal Epithelium in Male Wistar Rats. Bull. Exp. Biol. Med. 2015;158(3):380-384. doi: https://doi.org/10.1007/s10517-015-2767-2

    Article  CAS  PubMed  Google Scholar 

  4. Diatroptov ME, Slesarev SM, Slesareva EV. Characteristics of 4-Day Infradian Biorhythms in Mature Male Wistar Rats after Pinealectomy. Bull. Exp. Biol. Med. 2017;163(1):109-113. doi: https://doi.org/10.1007/s10517-017-3749-3

    Article  CAS  PubMed  Google Scholar 

  5. Zilov VG, Subbotina TI, Yashin AA, Khadartsev AA, Ivanov DV. Effects of Electromagnetic Fields Modulated by Infralow Frequencies on the Production of Stem Cells. Bull. Exp. Biol. Med. 2018;164(5):685-687. doi: https://doi.org/10.1007/s10517-018-4059-0

    Article  CAS  PubMed  Google Scholar 

  6. Martynyuk VS, Temur’yants NA. Extremely low frequency magnetic fields as a modulation factor and synchronization of infradian biorhythms in animals. Geofiz. Protsessy Biosfera. 2009;8(1):36-50. Russian.

    Google Scholar 

  7. Ogai VB, Novoselova EG, Fesenko EE. Effect of weak super-high and extremely high frequency electromagnetic radiation on the proliferative and cytotoxic activity of murine spleen lymphocytes. Biophysics. 2003;48(3):483-491.

    Google Scholar 

  8. Freshney RI. Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications. Moscow, 2011. Russian.

  9. Cherry N. Schumann resonances, a plausible biophysical mechanism for the human health effects of Solar/Geomagnetic activity. Nat. Hazards. 2002;26(3):279-331.

    Google Scholar 

  10. Dronca RS, Leontovich AA, Nevala WK, Markovic SN. Personalized therapy for metastatic melanoma: could timing be everything? Future Oncol. 2012;8(11):1401-1406.

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Focan C, Cornélissen G, Halberg F. Chronometaanalysis: circasemiseptan (3.5-day) pattern in mitotic activity of murine sarcoma after treatment with cyclophosphamide. In Vivo;9(4):401-406.

  12. Jozsa R, Olah A, Cornélissen G, Csernus V, Otsuka K, Zeman M, Nagy G, Kaszaki J, Stebelova K, Csokas N, Pan W, Herold M, Bakken EE, Halberg F. Circadian and extracircadian exploration during daytime hours of circulating corticosterone and other endocrine chronomes. Biomed. Pharmacother. 2005;59(Suppl. 1):S109-S116.

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Maschke C, Harder J, Cornélissen G, Hecht K, Otsuka K, Halberg F. Chronoecoepidemiology of “strain”: infradian chronomics of urinary cortisol and catecholamines during nightly exposure to noise. Biomed. Pharmacother. 2003;57(Suppl. 1):126s-135s.

    CAS  Google Scholar 

  14. Selmaoui B, Touitou Y. Age-related differences in serum melatonin and pineal NAT activity and in the response of rat pineal to a 50-Hz magnetic field. Life Sci. 1999;64(24):2291-2297.

    CAS  PubMed  Google Scholar 

  15. Weydahl A, Sothern RB, Cornélissen G, Wetterberg L. Geomagnetic activity influences the melatonin secretion at latitude 70 degrees N. Biomed. Pharmacother. 2001;55(Suppl. 1):57s-62s.

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Research Institute of Human Morphology, Moscow, Russia

    M. A. Diatroptova & E. A. Ponomarenko

  2. A. N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, Russia

    M. E. Diatroptov

Authors
  1. M. A. Diatroptova
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  2. E. A. Ponomarenko
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  3. M. E. Diatroptov
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Correspondence to M. E. Diatroptov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 169, No. 5, pp. 648-652, May, 2020

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Diatroptova, M.A., Ponomarenko, E.A. & Diatroptov, M.E. Infradian Rhythm in Proliferative Activity of a Culture of Embryonic Fibroblast-Like Cells from C57BL/6 Mice. Bull Exp Biol Med 169, 714–717 (2020). https://doi.org/10.1007/s10517-020-04962-y

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  • DOI: https://doi.org/10.1007/s10517-020-04962-y

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