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Composition and Structure of Gut Microbiome in Adolescents with Obesity and Different Breastfeeding Duration

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Gut microbiome of adolescents with obesity and different duration of breastfeeding was analyzed by metagenomic analysis of V3-V4 variable domains of the 16S rRNA gene. In subgroup with breastfeeding duration <3 months, intrapopulation structure of gut microbiome by alpha diversity indices was similar in adolescents with obesity and normal body weight. The decrease in phylotype abundance in the structure of communities was associated only with obesity, while dysbiotic state persisted in both lean and overweight adolescents, which confirmed the effect of breastfeeding duration on stability of gut microbiome.

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Authors and Affiliations

  1. Research Center for Family Health and Human Reproduction Problems, Irkutsk, Russia

    N. L. Belkova, U. M. Nemchenko, A. V. Pogodina, A. I. Romanitsa, E. A. Novikova & L. V. Rychkova

  2. Limnological Institute, Siberian Division of the Russian Academy of Sciences, Irkutsk, Russia

    N. L. Belkova & S. I. Feranchuk

  3. Irkutsk National Research Technical University, Irkutsk, Russia

    S. I. Feranchuk

Authors
  1. N. L. Belkova
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  2. U. M. Nemchenko
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  3. A. V. Pogodina
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  4. S. I. Feranchuk
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  5. A. I. Romanitsa
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  6. E. A. Novikova
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  7. L. V. Rychkova
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Corresponding author

Correspondence to N. L. Belkova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 167, No. 6, pp. 717-721, June, 2019

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Belkova, N.L., Nemchenko, U.M., Pogodina, A.V. et al. Composition and Structure of Gut Microbiome in Adolescents with Obesity and Different Breastfeeding Duration. Bull Exp Biol Med 167, 759–762 (2019). https://doi.org/10.1007/s10517-019-04617-7

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  • DOI: https://doi.org/10.1007/s10517-019-04617-7

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