The effects of helium cold plasma on some parameters of metabolism of rat erythrocytes were studied after a course exposure (10 daily procedures, 1 min each). The intensity of free-radical processes in erythrocyte membranes, malondialdehyde concentration, and aldehyde dehydrogenase activity were analyzed. The exposure to helium cold plasma led to a significant increase in malondialdehyde level mostly associated with inhibition of its utilization. These changes were not related to activation of malondialdehyde synthesis in LPO reactions.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Aleinik AN. Plasma Medicine. Tomsk, 2011. Russian.
Martusevich AK, Soloveva AG, Yanin DV, Galka AG, Krasnova SYu. The influence of helium cold plasma on the parameters of blood oxidative metabolism in vitro. Vestn. Nov. Med. Tekhnol. 2017;24(3):163-166. Russian.
Kershengol’ts BM, Serkina EV. Some mathematical approaches to analysis of ethanol metabolism. Lab. Delo. 1981;(2):126. Russian.
Alkawareek MY, Gorman SP, Graham W.G, Gilmore B.F. Potential cellular targets and antibacterial efficacy of atmospheric pressure non-thermal plasma. Int J. Antimicrob. Agents. 2014;43(2):154-160.
Brun P, Pathak S, Castagliuolo I, Palù G, Brun P, Zuin M, Cavazzana R, Martines E. Helium generated cold plasma finely regulates activation of human fibroblast-like primary cells. PLoS One. 2014;9(8):e104397. doi: https://doi.org/10.1371/journal.pone.0104397.
Dobrynin D, Friedman G, Fridman G, Fridman A. Physical and biological mechanisms of direct plasma interaction with living tissue. New J. Phys. 2009;11. ID 115020. doi: https://doi.org/10.1088/1367-2630/11/11/115020.
Ermolaeva SA, Varfolomeev AF, Chernukha MY, Yurov DS, Vasiliev MM, Kaminskaya AA, Moisenovich MM, Romanova JM, Murashev AN, Selezneva II, Shimizu T, Sysolyatina EV, Shaginyan IA, Petrov OF, Mayevsky EI, Fortov VE, Morfill GE, Naroditsky BS, Gintsburg AL. Bactericidal effects of nonthermal argon plasma in vitro, in biofilms and in the animal model of infected wounds. J. Med. Microbiol. 2011;60(Pt 1):75-83.
Flynn PB, Busetti A, Wielogorska E, Chevallier OP, Elliott CT, Laverty G, Gorman SP, Graham WG, Gilmore BF. Nonthermal plasma exposure rapidly attenuates bacterial AHL-dependent quorum sensing and virulence. Sci. Rep. 2016;6. ID 26320. doi: https://doi.org/10.1038/srep26320.
Hoffmann C, Berganza C, Zhang J. Cold atmospheric plasma: methods of production and application in dentistry and oncology. Med. Gas Res. 2013;3(1):21. doi: https://doi.org/10.1186/2045-9912-3-21.
Jawaid P, Rehman MU, Zhao QL, Takeda K, Ishikawa K, Hori M, Shimizu T, Kondo T. Helium-based cold atmospheric plasma-induced reactive oxygen species-mediated apoptotic pathway attenuated by platinum. J. Cell. Mol. Med. 2016;20(9):1737-1748.
Wiegand C, Fink S, Beier O, Horn K, Pfuch A, Schimanski A, Grünler B, Hipler UC, Elsner P. Dose- and time-dependent cellular effects of cold atmospheric pressure plasma evaluated in 3D skin models. Skin Pharmacol. Physiol. 2016;29(5):257-265.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 167, No. 2, pp. 144-146, February, 2019
Rights and permissions
About this article
Cite this article
Martusevich, A.K., Solov’eva, A.G., Galka, A.G. et al. Effects of Helium Cold Plasma on Erythrocyte Metabolism. Bull Exp Biol Med 167, 198–200 (2019). https://doi.org/10.1007/s10517-019-04490-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-019-04490-4