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In Vitro Study of the Modulatory Effects of Levofloxacin and BCG on Secretion of Proinflammatory Cytokines in Infiltrative Pulmonary Tuberculosis

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Bulletin of Experimental Biology and Medicine Aims and scope

The effects levofloxacin (fluoroquinolone) and vaccinal BCG strain on cytokine production by blood mononuclear leukocytes was studied in patients with infiltrative pulmonary tuberculosis. Combined treatment with levofloxacin and vaccinal BCG strain suppressed the production of TNFα in drug-resistant pulmonary tuberculosis and production of IL-12 and IFNγ in drug-sensitive tuberculosis.

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Authors and Affiliations

  1. Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia

    V. A. Serebryakova, O. I. Urazova, V. V. Novitsky, A. I. Vengerovskii & T. E. Kononova

Authors
  1. V. A. Serebryakova
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  2. O. I. Urazova
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  3. V. V. Novitsky
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  4. A. I. Vengerovskii
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  5. T. E. Kononova
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Corresponding author

Correspondence to V. A. Serebryakova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 166, No. 8, pp. 182-185, August, 2018

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Serebryakova, V.A., Urazova, O.I., Novitsky, V.V. et al. In Vitro Study of the Modulatory Effects of Levofloxacin and BCG on Secretion of Proinflammatory Cytokines in Infiltrative Pulmonary Tuberculosis. Bull Exp Biol Med 166, 225–228 (2018). https://doi.org/10.1007/s10517-018-4319-z

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  • DOI: https://doi.org/10.1007/s10517-018-4319-z

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