Bacterial biofilms provoke and/or promote the most chronic and recurrent infectious diseases. Previously, experimental models of purulent peritonitis and meningoencephalitis revealed positive antibiofilm effect of metallic nanoparticles and the absence of resistance against such nanoparticles in microorganisms. This study examines the combined effect of silver nanoparticles with ceftriaxone and methyluracil on recovery mechanisms during inflammatory diseases exemplified by purulent peritonitis in experimental animals.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Savin EI, Subbotina TI, Khadartsev AA, Khrenov PA, Tchesnova TV, Buzulukov YuP, Antsiferova AN. Experimental study of antibacterial activity of silver nanoparticles on the model of peritonitis and meningoencephalitis in vivo. Vestn. Nov. Med. Tekhnol. Elektron. Izdanie. 2014;(1):35. Russian.
Seryogina NV, Chestnova TV. The peculiarities of bacterium existence in biofilm by the example of urinary pathogenic bacillus. Vestn. Nov. Med. Tekhnol. 2010;17(4):28-30. Russian.
Seregina NV, Tchestnova TV, Prokoptchenko DV, Chromushin VA. Review of Analitic Studies about Physico- Chemistry Biology of Shungit. Vestn. Nov. Med. Tekhnol. 2008;15(4):171-173. Russian.
Khrenov PA, Chestnova TV, Gladkikh PG. Adhesion potential of gram-negative flora of the wound under the influence of “Dimexidum”. Mezhdunarod. Zh. Prikl. Fundament. Issled. 2014;(1):92. Russian.
Khrenov PA, Chestnova TV, Gladkikh PG. Effect of dimethyl sulfoxide on biofilm formation by Staphylococcus aureus strains. Mezhdunarod. Zh. Prikl. Fundament. Issled. 2014; (5-1):140-141. Russian.
Khrenov PA, Tchestnova PA, Seregina PA, Gladkikh PG, Maslov MS. The study in vitro the virulence properties and resistance to antimycotic drugs of fungi Candida isolated from children with acute intestinal infection. Vestn. Nov. Med. Tekhnol. Elektron. Izdanie. 2014;(1):92. Russian.
Khromushin VA, Tchesnova TV, Platonov VV, Khadartsev AA, Kireev SS. The shungite as natural nanotechnologie (literature review). Vestn. Nov. Med. Tekhnol. Elektron. Izdanie. 2014;(1):162. Russian.
Chestnova TV, Gladkikh PG, Korotkova AS. Change adhesion S. aureus as a factor of recovery regenerative activity at the hearing purulent wounds. Vestn. Nov. Med. Tekhnol. Elektron. Izdanie. 2017;(3):74-77. Russian.
Chestnova TV, Gladkikh PG, Korotkova AS. Effect of silver nanoparticles in combination with methyluracil on the biofilms in an experimental model of peritonitis in rats. Vestn. Nov. Med. Tekhnol. Elektron. Izdanie. 2017;(3):60-69. Russian.
Chestnova TV, Gladkikh PG, Korotkova AS. Effectiveness of dimethylsulphoxide on biofilm formation by Staphylococcus aureus strains, as the indicator of recovery reactions for purulent-inflammatory processes. Vestn. Nov. Med. Tekhnol. Elektron. Izdanie. 2017;(3):70-73. Russian.
Khrenov PA, Chestnova TV. Influence of dimethylsulfoxide on the adhesive activity Staphylococcus aureus isolated from the wounds. Int. J. Exp. Edu. 2013;(6):47.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 165, No. 6, pp. 737-741, June, 2018
Rights and permissions
About this article
Cite this article
Chestnova, T.V., Zilov, V.G., Gladkikh, P.G. et al. Combined Effect of Silver Nanoparticles, Ceftriaxone, and Methyluracil during Experimental Purulent Peritonitis. Bull Exp Biol Med 165, 777–780 (2018). https://doi.org/10.1007/s10517-018-4262-z
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-018-4262-z