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Activity of Cathepsin B and Proteome in the Serum and Brain of Rats with Different Behavioral Activity under Conditions of Metabolic Stress

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Bulletin of Experimental Biology and Medicine Aims and scope

Study of the brain and serum of male Wistar rats with the metabolic stress model detected changed proteomic profiles of emotiogenic structures and an increase of cathepsin B activity. Antiapoptotic effect of coenzyme Q10, added to the ration, was detected. Differences in the adaptation response of animals with passive and active behavior under conditions of metabolic stress were detected.

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Authors and Affiliations

  1. Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

    N. V. Kirbaeva, A. D. Malinkin & A. V. Vasil’ev

  2. V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia

    N. E. Sharanova

Authors
  1. N. V. Kirbaeva
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  2. N. E. Sharanova
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  3. A. D. Malinkin
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  4. A. V. Vasil’ev
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Corresponding author

Correspondence to N. V. Kirbaeva.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 165, No. 6, pp. 676-680, June, 2018

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Kirbaeva, N.V., Sharanova, N.E., Malinkin, A.D. et al. Activity of Cathepsin B and Proteome in the Serum and Brain of Rats with Different Behavioral Activity under Conditions of Metabolic Stress. Bull Exp Biol Med 165, 721–724 (2018). https://doi.org/10.1007/s10517-018-4250-3

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  • DOI: https://doi.org/10.1007/s10517-018-4250-3

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