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New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins

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Bulletin of Experimental Biology and Medicine Aims and scope

During metastatic growth, cells of solid tumors undergo phenotypical changes related to epithelial-mesenchymal transition. Epithelial-mesenchymal transition is regarded as a potential target for prospective antitumor drugs. Fluorescent reporter systems for evaluation of the expression of markers of epithelial and mesenchymal status (E- and N-cadherins) were created. The described approaches can be used for creation of analogous reporter systems.

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Authors and Affiliations

  1. BioClinicum Center, Moscow, Russia

    O. A. Burmistrova, S. V. Nikulin & G. S. Zakharova

  2. P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation, Moscow, Russia

    K. A. Fomicheva, B. Ya. Alekseev & M. Yu. Shkurnikov

Authors
  1. O. A. Burmistrova
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  2. S. V. Nikulin
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  3. G. S. Zakharova
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  4. K. A. Fomicheva
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  5. B. Ya. Alekseev
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  6. M. Yu. Shkurnikov
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Corresponding author

Correspondence to O. A. Burmistrova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 165, No. 1, pp. 104-109, January, 2018

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Burmistrova, O.A., Nikulin, S.V., Zakharova, G.S. et al. New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins. Bull Exp Biol Med 165, 88–93 (2018). https://doi.org/10.1007/s10517-018-4106-x

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  • DOI: https://doi.org/10.1007/s10517-018-4106-x

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