Repeated administration of songorine to mice restored mnestic processes impaired by scopolamine treatment, which manifested in improvement of CPAR conditioning and normalization of behavioral activity throughtout the observation period. This thearpeutical effect surpassed that of pyracetam used as the reference drug.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 165, No. 1, pp. 15-19, January, 2018
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Nesterova, Y.V., Povet’eva, T.N., Suslov, N.I. et al. Correction of Cholinergic Abnormalities in Mnestic Processes with Diterpene Alkaloid Songorine. Bull Exp Biol Med 165, 10–13 (2018). https://doi.org/10.1007/s10517-018-4087-9
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DOI: https://doi.org/10.1007/s10517-018-4087-9