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Infrared Fluorescent Angiography during Experimental Trachea Transplantation

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Bulletin of Experimental Biology and Medicine Aims and scope

Indocyanine green fluorescence was used for evaluation of the degree of trachea revascularization after its autotransplantation in rabbits (transplantation of 1- and 2-cm segment of the trachea). Intravenous administration of indocyanine green was followed by a significant fluorescence of the substance in microvessels of the trachea over 30-40 sec. Immediately after surgery, fluorescence in the implanted segment was absent, but within 7 days it was completely restored in rabbits receiving transplantation of a 1-cm segment. After transplantation of 2-cm segment of the trachea, fluorescence did not recover, which corresponded to the clinical picture and autopsy results. Thus, fluorescent angiography is an informative method for evaluation of trachea revascularization.

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Authors and Affiliations

  1. I. P. Pavlov First St. Petersburg State Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia

    A. L. Akopov, G. V. Papayan, A. N. Efimov, V. O. Yaprintsev & M. A. Magruk

  2. Federal Research Center of Nutrition, Biotechnology, and Food Safety, Moscow, Russia

    D. B. Nikityuk

Authors
  1. A. L. Akopov
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  2. G. V. Papayan
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  3. A. N. Efimov
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  4. D. B. Nikityuk
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  5. V. O. Yaprintsev
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  6. M. A. Magruk
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Correspondence to A. L. Akopov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 164, No. 10, pp. 525-528, October 2017

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Akopov, A.L., Papayan, G.V., Efimov, A.N. et al. Infrared Fluorescent Angiography during Experimental Trachea Transplantation. Bull Exp Biol Med 164, 519–522 (2018). https://doi.org/10.1007/s10517-018-4024-y

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  • DOI: https://doi.org/10.1007/s10517-018-4024-y

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