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Effect of Vitrification on Functional Morphology and Viability of the Ovarian Tissue

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The results of a complex morphofunctional study with markers of proliferation (PCNA and Ki-67), angiogenesis (CD31 and CD34), and structural integrity of mesenchymal cells (vimentin) suggest that the pool of primordial follicles was well preserved in vitrified ovarian tissue and that viability of its cellular components can be rapidly restored during incubation at 37°C within 4 h after thawing.

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Authors and Affiliations

  1. A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Obninsk, Russia

    V. V. Yuzhakov, I. V. Malinova, M. V. Kiseleva, N. K. Fomina, L. N. Bandurko, E. V. Komarova, L. E. Sevan’kaeva, I. E. Ingel’, N. D. Yakovleva & A. D. Kaprin

Authors
  1. V. V. Yuzhakov
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  2. I. V. Malinova
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  3. M. V. Kiseleva
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  4. N. K. Fomina
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  5. L. N. Bandurko
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  6. E. V. Komarova
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  7. L. E. Sevan’kaeva
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  8. I. E. Ingel’
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  9. N. D. Yakovleva
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  10. A. D. Kaprin
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Corresponding author

Correspondence to I. V. Malinova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 164, No. 10, pp. 506-511, October, 2017

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Yuzhakov, V.V., Malinova, I.V., Kiseleva, M.V. et al. Effect of Vitrification on Functional Morphology and Viability of the Ovarian Tissue. Bull Exp Biol Med 164, 502–507 (2018). https://doi.org/10.1007/s10517-018-4021-1

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  • DOI: https://doi.org/10.1007/s10517-018-4021-1

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