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Functional and Biochemical Parameters of Erythrocytes during Mexicor Treatment in Posttraumatic Period after Experimental Blood Loss and Combined Traumatic Brain Injury

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Mexicor treatment (8 mg/kg body weight per day) during the posttraumatic period after concomitant traumatic brain injury and acute blood loss in rats increased electrophoretic mobility and concentration of 2,3-diphosphoglycerate, and reduced malondialdehyde content in erythrocytes. These changes improved hemodynamics and oxygen-transporting function of the blood. The most pronounced effects of Mexicor were observed at the early stages of posttraumatic period.

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Authors and Affiliations

  1. Department of Biochemistry and Physiology, N. I. Lobachevsky National Research Nizhny Novgorod State University, Nizhny Novgorod, Russia

    A. V. Deryugina, A. V. Shumilova, E. S. Filippenko & Ya. V. Galkina

  2. Department of Anesthesiology and Reanimatology, Municipal Clinical Hospital No. 40, Nizhny Novgorod, Russia

    I. S. Simutis

  3. Department of Anesthesiology and Reanimatology, Faculty of Continuing Medical Education, Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia

    G. A. Boyarinov

Authors
  1. A. V. Deryugina
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  2. A. V. Shumilova
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  3. E. S. Filippenko
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  4. Ya. V. Galkina
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  5. I. S. Simutis
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  6. G. A. Boyarinov
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Corresponding author

Correspondence to A. V. Deryugina.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 164, No. 7, pp. 34-37, July, 2017

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Deryugina, A.V., Shumilova, A.V., Filippenko, E.S. et al. Functional and Biochemical Parameters of Erythrocytes during Mexicor Treatment in Posttraumatic Period after Experimental Blood Loss and Combined Traumatic Brain Injury. Bull Exp Biol Med 164, 26–29 (2017). https://doi.org/10.1007/s10517-017-3918-4

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  • DOI: https://doi.org/10.1007/s10517-017-3918-4

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