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High Potassium Concentration during Culturing of Early Mammalian Embryos: Normal or Extreme Situation?

  • Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Analysis of the element composition of oviduct and uterine fluid in mammals showed high potassium concentrations in the early embryo microenvironment in vivo. The results of early embryogenesis of mammals in vitro in the presence of high potassium concentrations are discussed. The data are summarized in accordance with the conditions of experimentally modeled pre-implantation development. Comparative assessment of the quality of embryo development until the blastocyst stage in vitro proved the embryos more successfully developed at potassium concentrations close to those registered in the oviductal fluid.

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Authors and Affiliations

  1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia

    A. G. Pogorelov, A. A. Smirnov & V. N. Pogorelova

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  1. A. G. Pogorelov
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  2. A. A. Smirnov
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  3. V. N. Pogorelova
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Correspondence to A. G. Pogorelov.

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Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 1, pp. 55-60, January, 2017

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Pogorelov, A.G., Smirnov, A.A. & Pogorelova, V.N. High Potassium Concentration during Culturing of Early Mammalian Embryos: Normal or Extreme Situation?. Bull Exp Biol Med 163, 163–168 (2017). https://doi.org/10.1007/s10517-017-3758-2

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