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Systemic Amyloidosis Model on Young Mice

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Bulletin of Experimental Biology and Medicine Aims and scope

Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.

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Authors and Affiliations

  1. Department of Medical Biology with a Course of Microbiology and Virology, Cheboksary, Russia

    V. A. Kozlov, S. P. Sapozhnikov, A. I. Sheptukhina & O. V. Nikolaeva

  2. Department of Common, Clinical Pathology and Forensic Medicine, I. N. Ulyanov Chuvash State University, Cheboksary, Russia

    P. B. Karyshev

Authors
  1. V. A. Kozlov
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  2. S. P. Sapozhnikov
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  3. P. B. Karyshev
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  4. A. I. Sheptukhina
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  5. O. V. Nikolaeva
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Corresponding author

Correspondence to V. A. Kozlov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 10, pp. 523-527, October, 2016

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Kozlov, V.A., Sapozhnikov, S.P., Karyshev, P.B. et al. Systemic Amyloidosis Model on Young Mice. Bull Exp Biol Med 162, 520–523 (2017). https://doi.org/10.1007/s10517-017-3652-y

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  • DOI: https://doi.org/10.1007/s10517-017-3652-y

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