Structural characteristics of the vaginal mucosa in stress incontinence and its correction by IncontiLase technology were studied. Studies of vaginal biopsy specimens before the exposure showed degenerative and atrophic changes in the stratified squamous epithelium, disorganization of fibrillar structures of the intercellular matrix, and microcirculatory disorders. Studies after Er:YAG laser exposure showed signs of neocollagenogenesis and elastogenesis, foci of neoangiogenesis, reduction of epithelial degeneration and atrophy, and an increase of the fibroblast population. Morphometry showed that the volume density of blood capillaries and the thickness of the epithelial layer increased by 61.1 and 64.5%, respectively. The use of IncontiLase technology in stress incontinence led to structural reorganization of the vaginal mucosa, improving its morphology and function and alleviating the symptoms of incontinence.
This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Tax calculation will be finalised during checkout.
Apolikhina IA, Gorbunova EA, Odinokova VA. The role and place of minimally invasive innovative laser technologies in gynecological practice. Akush. Gin. 2014;(11):17-22. Russian.
Apolikhina IA, Konstantinov VV, Deev AD. Prevalence and social aspects of urinary incontinence in women. Akush. Gin. 2005;(5):32-36. Russian.
Bezmenko AA, Shmidt AA, Koval’ AA, Karpishchenko ZhM. Conservative methods of treatment of urinary incontinence at strain at women. Vestn. Ross. Voen.-Med. Akad. 2014;45(1):227-232. Russian.
Kulakov VI, Savel’eva GM, Manukhin IB. Gynecology. National Guidlines. Moscow, 2009. Russian.
Leshunov EV, Martov AG. Application of laser technologies for treatment of urinary stress incontinence in women of reproductive age. Urologiya. 2015;(1):36-40. Russian.
Neimark AI, Razdorskaya MV. Urinary Incontinence at Women. Moscow, 2013. Russian.
Yakovleva AY, Neymark AI, Lapiy GA. Application of laser technologies for treatment of stressful urinary incontience at women. Med. Obrazov. Sibiri. 2014;(5):33-38. Russian.
Fistonić N, Fistonić I, Lukanovič A, Findri Guštek Š, Sorta Bilajac Turina I, Franić D. First assessment of short-term efficacy of Er:YAG laser treatment on stress urinary incontinence in women: prospective cohort study. Climacteric. 2015;18(Suppl. 1):37-42.
Minassian VA, Stewart WF, Wood GC. Urinary incontinence in women: variation in prevalence estimates and risk factors. Obstet. Gynecol. 2008;111(2, Pt 1):324-331.
Ogrinc UB, Senčar S, Lenasi H. Novel minimally invasive laser treatment of urinary incontinence in women. Lasers Surg. Med. 2015;47(9):689-697.
Salvatore S, Leone Roberti Maggiore U, Athanasiou S, Origoni M, Candiani M, Calligaro A, Zerbinati N. Histological study on the effects of microablative fractional CO2 laser on atrophic vaginal tissue: an ex vivo study. Menopause. 2015;22(8):845-849.
Sencar S, Bizjak-Ogrinc U. Laser treatment of stress urinary incontinence. J. Laser Health Acad. 2013;(1):S27.
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 10, pp. 511-516, October, 2016
About this article
Cite this article
Lapii, G.A., Yakovleva, A.Y. & Neimark, A.I. Structural Reorganization of the Vaginal Mucosa in Stress Urinary Incontinence under Conditions of Er:YAG Laser Treatment. Bull Exp Biol Med 162, 510–514 (2017). https://doi.org/10.1007/s10517-017-3650-0
- stress urinary incontinence
- IncontiLase Laser technology
- Er:YAG laser
- vaginal biopsy