The period of forming of superficial vascular plexus during physiological retinal angiogenesis was shorter in C57Bl/6 mice. Experiments on the model of oxygen-induced retinopathy showed that avascular and vascularized zones in BALB/c mice on day 17 are smaller than in C57Bl/6 mice are by 5 and 1.5 times, respectively. The obtained results confirmed the importance of phenotype of retinal macrophages in the regulation of processes of both physiological and pathological retinal angiogenesis.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 8, pp. 145-147, August, 2016
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Lyamina, S.V., Komova, O.Y., Gavrilova, N.A. et al. Effects of Phenotype of Retinal Macrophages on the Features of Angiogenesis of Murine Retina. Bull Exp Biol Med 162, 184–186 (2016). https://doi.org/10.1007/s10517-016-3571-3
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DOI: https://doi.org/10.1007/s10517-016-3571-3