Skip to main content
Log in

Effectiveness of Lifestyle Modification in Corrections of States Associated with Metabolic Syndrome

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

In a 3-month study, 30 obese patients were assigned to lifestyle modification therapy, which is the major component of all modern strategies correcting the metabolic syndrome. The 3-month course of non-pharmacological therapy significantly diminished the major index evaluating the state of these patients, i.e., the risk of cardiovascular disasters. This therapy positively affected all the states associated with metabolic syndrome: arterial BP attained the targets in 53% patients together with normalization of their nocturnal arterial BP dipping status; the lipid panel and carbohydrate metabolic indices normalized in 46 and 44% patients, respectively; hepatic steatosis moderated in 56% patients; and the disturbances in hemostasis were annihilated in 67% patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. European guidelines on prevention of cardiovascular disease in clinical practice (revised in 2012). Ross. Kardiol. Zh. 2012(4, Suppl. 2). Russian.

  2. Kalashnikova MF. Metabolic syndrome: a modern view on concept, prevention methods and treatment. Effekt. Farmakoter. 2013(52):52-63. Russian.

    Google Scholar 

  3. Prevention of cardiovascular diseases. Recommendations of All-Russian Scientific Cardiological Society. Kardiovaskular. Ter. Prof. 2011;10(6, Suppl. 2). Russian.

  4. Kovaleva ON. Clinical effects of lifestyle modifi cation in obesity. Zdorov’e Ukrainy. 2007;10(1):68-69. Russian.

    Google Scholar 

  5. Kseneva IS, Yurmazov ZA, Udut VV. Effect of non-pharmacological correction of metabolic syndrome on the condition of the prostate gland in young patients. Evraz. Soyuz Uchenykh. 2016(2, Pt 2):64-66. Russian.

  6. Mekhtiev SN, Grinevich VB, Kravchuk YuA, Brashchenkova AV. Nonalcoholic fatty liver disease: clinical features, diagnosis, and treatment. Lech. Vrach. 2008(2):29-37. Russian.

  7. American Diabetes association. Standards of medical care in diabetes. Diabetes Care. 2008;31(Suppl. 1):12-54.

    Article  Google Scholar 

  8. Bastien M, Poirier P, Lemieux I, Després JP. Overview of epidemiology and contribution of obesity to cardiovascular disease. Prog. Cardiovasc. Dis. 2014;56(4):369-381.

    Article  PubMed  Google Scholar 

  9. Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M; STOP-NIDDM Trial Research Group. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOPNIDDM trial. JAMA. 2003;290(4):486-494.

    Article  CAS  PubMed  Google Scholar 

  10. Lindström J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, Uusitupa M, Tuomilehto J; Finnish Diabetes Prevention Study Group. The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care. 2003;26(12):3230-3236.

    Article  PubMed  Google Scholar 

  11. Solovyev MA, Tutrin II, Udut VV, Borodulina EV, Turenko AV. Global tests evaluating the functional condition of hemostasis. J. Clin. Exp. Pharmacol. 2015;5:178. doi:10.4172/2161-1459.1000178.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. I. Kseneva.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 7, pp. 46-49, July, 2016

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kseneva, S.I., Borodulina, E.V., Trifonova, O.Y. et al. Effectiveness of Lifestyle Modification in Corrections of States Associated with Metabolic Syndrome. Bull Exp Biol Med 162, 38–41 (2016). https://doi.org/10.1007/s10517-016-3539-3

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-016-3539-3

Key Words

Navigation