Skip to main content
Log in

Features of the Left Ventricular Functional Geometry in Patients with Myocardial Diseases with Varying Degrees of Systolic Dysfunction

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

We revealed some features of the left ventricular functional geometry in patients with myocardial diseases with different degrees of left ventricular systolic dysfunction. A negative correlation was found between the spatio-temporal heterogeneity of the kinetics of the left ventricular wall during systole and ejection fraction in normal heart and in systolic dysfunction. The differences in the quantitative characteristics of the functional geometry between patients and normal subjects and between different groups of patients depended on the severityof left-ventricular systolic dysfunction. In particular, spatial heterogeneity index that characterizes heterogeneity of systolic movement of the wall segments and end-systolic Fourier shape-power index characterizing complexity of the left ventricle shape during systole differed significantly in the examined groups of patients and have the greatest diagnostic power.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Chumarnaya T, Solovyova O, Alueva Y, Mikhailov SP, Kochmasheva VV, Markhasin VS. Left Ventricle Functional Geometry in Cardiac Pathology. Computing in Cardiology. 2015;42:353-356.

    Google Scholar 

  2. Chumarnaia TV, Solov’eva OE, Sukhareva SV, Vargina TA, Markhasin VS. Spatio-temporal heterogeneity of human left ventricle contractions in norm and under ischemic heart disease. Ross. Fiziol. Zh. Im. I. M. Sechenova. 2008;94(11):1217-1239.

    CAS  PubMed  Google Scholar 

  3. Di Donato M, Dabic P, Castelvecchio S, Santambrogio C, Brankovic J, Collarini L, Joussef T, Frigiola A, Buckberg G, Menicanti L; RESTORE Group. Left ventricular geometry in normal and post-anterior myocardial infarction patients: sphericity index and ‘new’ conicity index comparisons. Eur. J. Cardiothorac. Surg. 2006;29(Suppl 1):S225-S230.

    Article  Google Scholar 

  4. Fawcett T. An introduction to ROC analysis. Pattern Recognit. Lett. 2006;27:861-874.

    Article  Google Scholar 

  5. Markhsin VS, Solov’eva O, Chumarnaia TV, Sukhareva SV. The problem of myocardial heterogeneity. Ross. Fiziol. Zh. Im. I. M. Sechenova. 2009;95(9):919-943.

    CAS  PubMed  Google Scholar 

  6. Sengupta PP, Korinek J, Belohlavek M, Narula J, Vannan MA, Jahangir A, Khandheria BK. Left ventricular structure and function: basic science for cardiac imaging. J. Am. Coll. Cardiol. 2006;48(10):1988-2001.

    Article  PubMed  Google Scholar 

  7. Solovyova OE, Kraeva OA, Ivanova LV, Filimonova IM, Tsyvian PB, Kovtun OP, Markhasin VS. Functional geometry of human left ventriculum in ontogenesis. Dokl. Biol. Sci. 2011;439:204-207.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to T. V. Chumarnaya.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 7, pp. 37-41, July, 2016

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chumarnaya, T.V., Alueva, Y.S., Kochmasheva, V.V. et al. Features of the Left Ventricular Functional Geometry in Patients with Myocardial Diseases with Varying Degrees of Systolic Dysfunction. Bull Exp Biol Med 162, 30–34 (2016). https://doi.org/10.1007/s10517-016-3537-5

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-016-3537-5

Key Words

Navigation