We revealed some features of the left ventricular functional geometry in patients with myocardial diseases with different degrees of left ventricular systolic dysfunction. A negative correlation was found between the spatio-temporal heterogeneity of the kinetics of the left ventricular wall during systole and ejection fraction in normal heart and in systolic dysfunction. The differences in the quantitative characteristics of the functional geometry between patients and normal subjects and between different groups of patients depended on the severityof left-ventricular systolic dysfunction. In particular, spatial heterogeneity index that characterizes heterogeneity of systolic movement of the wall segments and end-systolic Fourier shape-power index characterizing complexity of the left ventricle shape during systole differed significantly in the examined groups of patients and have the greatest diagnostic power.
Similar content being viewed by others
References
Chumarnaya T, Solovyova O, Alueva Y, Mikhailov SP, Kochmasheva VV, Markhasin VS. Left Ventricle Functional Geometry in Cardiac Pathology. Computing in Cardiology. 2015;42:353-356.
Chumarnaia TV, Solov’eva OE, Sukhareva SV, Vargina TA, Markhasin VS. Spatio-temporal heterogeneity of human left ventricle contractions in norm and under ischemic heart disease. Ross. Fiziol. Zh. Im. I. M. Sechenova. 2008;94(11):1217-1239.
Di Donato M, Dabic P, Castelvecchio S, Santambrogio C, Brankovic J, Collarini L, Joussef T, Frigiola A, Buckberg G, Menicanti L; RESTORE Group. Left ventricular geometry in normal and post-anterior myocardial infarction patients: sphericity index and ‘new’ conicity index comparisons. Eur. J. Cardiothorac. Surg. 2006;29(Suppl 1):S225-S230.
Fawcett T. An introduction to ROC analysis. Pattern Recognit. Lett. 2006;27:861-874.
Markhsin VS, Solov’eva O, Chumarnaia TV, Sukhareva SV. The problem of myocardial heterogeneity. Ross. Fiziol. Zh. Im. I. M. Sechenova. 2009;95(9):919-943.
Sengupta PP, Korinek J, Belohlavek M, Narula J, Vannan MA, Jahangir A, Khandheria BK. Left ventricular structure and function: basic science for cardiac imaging. J. Am. Coll. Cardiol. 2006;48(10):1988-2001.
Solovyova OE, Kraeva OA, Ivanova LV, Filimonova IM, Tsyvian PB, Kovtun OP, Markhasin VS. Functional geometry of human left ventriculum in ontogenesis. Dokl. Biol. Sci. 2011;439:204-207.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 7, pp. 37-41, July, 2016
Rights and permissions
About this article
Cite this article
Chumarnaya, T.V., Alueva, Y.S., Kochmasheva, V.V. et al. Features of the Left Ventricular Functional Geometry in Patients with Myocardial Diseases with Varying Degrees of Systolic Dysfunction. Bull Exp Biol Med 162, 30–34 (2016). https://doi.org/10.1007/s10517-016-3537-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-016-3537-5