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Relationship between Morphofunctional Changes in Open Traumatic Brain Injury and the Severity of Brain Damage in Rats

  • MORPHOLOGY AND PATHOMORPHOLOGY
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Bulletin of Experimental Biology and Medicine Aims and scope

A correlation between the severity of morphofunctional disturbances and the volume of brain tissue injury determined by MRT was demonstrated on the model of open traumatic brain injury in rats. A relationship between the studied parameters (limb placing and beam walking tests and histological changes) and impact force (the height of load fell onto exposed brain surface) was revealed.

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Authors and Affiliations

  1. Hospital for Incurable Patients, Research Medical and Rehabilitation Center, Moscow, Russia

    F. M. Shakova, I. V. Barskov, M. V. Gulyaev, S. V. Prokhorenko, G. A. Romanova & A. V. Grechko

  2. Institute of Pathology and Pathomorphology, Moscow, Russia

    F. M. Shakova, I. V. Barskov & G. A. Romanova

  3. Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University, Moscow, Russia

    M. V. Gulyaev

Authors
  1. F. M. Shakova
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  2. I. V. Barskov
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  3. M. V. Gulyaev
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  4. S. V. Prokhorenko
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  5. G. A. Romanova
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  6. A. V. Grechko
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Corresponding author

Correspondence to F. M. Shakova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 161, No. 3, pp. 399-404, March, 2016

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Shakova, F.M., Barskov, I.V., Gulyaev, M.V. et al. Relationship between Morphofunctional Changes in Open Traumatic Brain Injury and the Severity of Brain Damage in Rats. Bull Exp Biol Med 161, 419–424 (2016). https://doi.org/10.1007/s10517-016-3429-8

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  • DOI: https://doi.org/10.1007/s10517-016-3429-8

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