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Oxidative Stress and Catalase Gene

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We studied the frequency of alleles and genotypes of CAT gene -262C>T polymorphism (rs1001179) in Russian and Buryat adolescents. The frequency of -262T allele was 28.31% in Russians and 16.84% in Buryats (p<0.01). In both ethnic groups, a correlation between the study polymorphism and concentration of diene conjugates was observed. Carriers of TT-genotype of CAT gene-262C>T polymorphism had lower level of diene conjugates than carriers of CT- and CC-genotypes.

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Authors and Affiliations

  1. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia

    O. A. Ershova, T. A. Bairova, S. I. Kolesnikov, O. V. Kalyuzhnaya, M. A. Darenskaya & L. I. Kolesnikova

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  1. O. A. Ershova
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  2. T. A. Bairova
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  3. S. I. Kolesnikov
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  4. O. V. Kalyuzhnaya
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  5. M. A. Darenskaya
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  6. L. I. Kolesnikova
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Corresponding author

Correspondence to O. A. Ershova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 161, No. 3, pp. 378-381, March, 2016

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Ershova, O.A., Bairova, T.A., Kolesnikov, S.I. et al. Oxidative Stress and Catalase Gene. Bull Exp Biol Med 161, 400–403 (2016). https://doi.org/10.1007/s10517-016-3424-0

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  • DOI: https://doi.org/10.1007/s10517-016-3424-0

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