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Soft Tissue Regeneration under the Effect of Wound Coating Based on Chitosan (Natural Biopolymer)

  • BIOTECHNOLOGIES
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Bulletin of Experimental Biology and Medicine Aims and scope

We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and buffer component, the biodegraded wound coating optimizes all phases of the wound process, accelerates by 22-28% the reparative regeneration, and leads to anatomic and functional restoration of injured sites. High absorption capacity recommends its use in the treatment of wounds with profuse exudation.

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Authors and Affiliations

  1. Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Saratov, Russia

    E. V. Gladkova, I. V. Babushkina, I. A. Norkin, I. A. Mamonova, D. M. Puchin’yan & E. A. Konyuchenko

Authors
  1. E. V. Gladkova
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  2. I. V. Babushkina
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  3. I. A. Norkin
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  4. I. A. Mamonova
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  5. D. M. Puchin’yan
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  6. E. A. Konyuchenko
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Corresponding author

Correspondence to E. V. Gladkova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 11, pp. 672-675, November, 2015

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Gladkova, E.V., Babushkina, I.V., Norkin, I.A. et al. Soft Tissue Regeneration under the Effect of Wound Coating Based on Chitosan (Natural Biopolymer). Bull Exp Biol Med 160, 715–717 (2016). https://doi.org/10.1007/s10517-016-3258-9

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  • DOI: https://doi.org/10.1007/s10517-016-3258-9

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