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A Hardware-and-Software System for Experimental Studies of the Acoustic Startle Response in Laboratory Rodents

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Bulletin of Experimental Biology and Medicine Aims and scope

We developed and tested a novel hardware-and-software system for recording the amplitude of the acoustic startle response in rodents. In our experiments, the baseline indexes of acoustic startle response in laboratory rats and pre-stimulation inhibition under the standard delivery of acoustic stimulation were similar to those evaluated by other investigators on foreign devices. The proposed system is relatively cheap and provides the possibility of performing experiments on freely moving specimens. It should be emphasized that the results of studies can be processed with free-access software.

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References

  1. M. I. Maleto, E. F. Pevtsov, and A. S. Sigov, Otkrytoe Obrazovanie, No. 5, 58-66 (2009).

  2. Manual on Preclinical Studies of Medicinal Agents [in Russian], Ed. A. N. Mironov, Moscow (2012), Pt 1.

  3. T. Blumenthal, Startle Modification. Implication for Neuro-science, Cognitive Science and Clinical Science, Eds. M. E. Dawson, et al., Cambridge (1999), pp. 51-71.

  4. F. K. Graham, Attention and Orienting. Sensory and Motivational Processes, Eds. P. J. Lang, et al., Manwah, New Jersey (1997), pp. 417-452.

  5. N. R. Swerdlow and M. A. Geyer, Schizophr. Bull., 24, No. 2, 285-301 (1998).

    Article  CAS  PubMed  Google Scholar 

  6. N. R. Swerdlow, M. Weber, Y. Qu, et al., Psychopharmacology (Berl.), 199, No. 3, 331-388 (2008).

  7. B. Valsamis and S. Schmid, J. Vis. Exp., 55, e3446, doi: 10.3791/3446 (2011).

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Correspondence to E. F. Pevtsov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 10, pp. 403-407, October, 2015

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Pevtsov, E.F., Storozheva, Z.I., Proshin, A.T. et al. A Hardware-and-Software System for Experimental Studies of the Acoustic Startle Response in Laboratory Rodents. Bull Exp Biol Med 160, 410–413 (2016). https://doi.org/10.1007/s10517-016-3183-y

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  • DOI: https://doi.org/10.1007/s10517-016-3183-y

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