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Study of Subchronic Toxicity of Relatox on Sexually Immature Animals

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Bulletin of Experimental Biology and Medicine Aims and scope

Intramuscular injections of Relatox in therapeutic and toxic doses to young outbred laboratory rats for 14 days caused no changes in the peripheral blood and bone marrow parameters, serum biochemical parameters, and morphology of the major viscera. In the toxic dose, the drug caused local irritation (inflammation, atrophy, and sclerosis in muscle tissue). Regeneration processes started in muscle tissue 7 days after Relatox withdrawal.

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Correspondence to A. A. Churin.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 7, pp. 63-66, July, 2015

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Churin, A.A., Fomina, T.I., Ermolaeva, L.A. et al. Study of Subchronic Toxicity of Relatox on Sexually Immature Animals. Bull Exp Biol Med 160, 53–56 (2015). https://doi.org/10.1007/s10517-015-3096-1

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  • DOI: https://doi.org/10.1007/s10517-015-3096-1

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