Injection of 5-fluorouracil to animals caused a pronounced toxic effect. Therapeutic and preventive treatment with Salix viminalis leaf extract significantly reduced the negative effects of the antitumor drug: promoted recovery of the bone marrow, peripheral blood, and visceral parameters and prevented ulceration. Combined use of the cytostatic and Salix viminalis extract increased the efficiency of antitumor therapy.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 7, pp. 58-62, July, 2015
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Aksinenko, S.G., Suslov, N.I., Povet’eva, T.N. et al. Antitoxic Activity of Extract from Salix Viminalis Leaves under Conditions of 5-Fluorouracil Treatment. Bull Exp Biol Med 160, 49–52 (2015). https://doi.org/10.1007/s10517-015-3095-2
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DOI: https://doi.org/10.1007/s10517-015-3095-2