Parameters of LPO reflecting primary and end stages of oxidation and total antioxidant activity were evaluated in the seminal fluid of young fertile men living in Novosibirsk. By the results of andrological examination and spermogram analysis, various reproductive disorders and abnormal spermogram (pathospermia) were found in 48 patients. Shifts towards activation of prooxidant processes in LPO–antioxidant defense metabolic system were observed in men with reproductive disorders and pathospermia. The results of individual estimation of coefficient of oxidative stress, an integral parameter reflecting the balance in the LPO–antioxidant defense system, attest to the development of oxidative stress in men with reproductive disorders and pathospermia.
Similar content being viewed by others
References
S. I. Kolesnikov, S. M. Gavalov, A. A. Radionchenko, et al., Sib. Nauchn. Med. Zh., 16, No. 2, 75-84 (1996).
L. I. Kolesnikova, L. A. Grebenkina, M. A. Darenskaya, and B. Ya. Vlasov, Sib. Nauchn. Med. Zh., 32, No. 1, 58-66 (2012).
L. I. Kolesnikova, M. A. Darenskaya, L. A. Grebenkina, et al., Bull. Exp. Biol. Med., 154, No. 2, 203-205 (2012).
L. I. Kolesnikova, N. A. Kurashova, L. A. Grebenkina, et al., Zdorov’e. Med. Ekol. Nauka, 44, No. 1, 38-41 (2011).
M. N. Maslova, Ross. Fiziol. Zh., 91, No. 11, 1320-1328 (2005).
L. V. Osadchuk, M. A. Kleshcheva, N. D. Temnikov, et al., Andrologiya Genit. Khir., No. 3, 52-55 (2010).
L. I. Kolesnikova, L. A. Grebenkina, E. V. Osipova, et al., Software for Calculation of the Coefficient of Oxidative Stress Based on the Parameters of the System of Lipid Peroxidation–Antioxidant Defense in the Blood, State Registration Certificate for Software No. 2011617323, September 21, 2011.
WHO Recommendations for Laboratory investigation of Human Ejaculate and Interaction between Spermatozoids and Cervical Mucus [in Russian], Moscow (2001).
A. V. Semenyuk, L. I. Kolesnikova, V. Yu. Kulikov, et al., Klin. Lab. Diagnostika, No. 10, 607-609 (1982).
G. V. Ter-Avanesov, Problems of Reproductive Health in Men [in Russian], Moscow (2002).
L. N. Shantalova, L. V. Osadchuk, B. G. Dashiev, et al., Byull. Vostoch. Sib. Nauch. Tsentr Sib. Otdel. Ross. Akad. Med. Nauk, No. 6, 44-46 (2012).
M. López-Teijón, M. Elbaile, and J. G. Alvarez, Andrologia, 40, No. 5, 318-328 (2008).
K. R. Muthusami and P. Chinnaswamy, Fertil. Steril., 84, No. 4, 919-924 (2005).
K. P. Phillips and N. Tanphaichitr, Toxicol. Environ. Health B Crit. Rev., 11, Nos. 3-4, 188-220 (2008).
S. G. Selevan, L. Borkovec, V. L. Slott, et al., Environ. Health Perspect., 108, No. 9, 887-894 (2000).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 159, No. 6, pp. 697-700, June, 2015
Rights and permissions
About this article
Cite this article
Kolesnikova, L.I., Kurashova, N.A., Osadchuk, L.V. et al. Parameters of Pro- and Antioxidant Status in Ejaculate of Men of Fertile Age. Bull Exp Biol Med 159, 726–728 (2015). https://doi.org/10.1007/s10517-015-3059-6
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-015-3059-6