The number of CD3+CD56–HLA-G+ cells in the peripheral blood of breast cancer patients was shown to increase by 2 times. Our results and published data suggest that the increase in the relative content of CD3+CD56–HLA-G+ cells in the circulating blood in breast cancer contributes to tumor development due to suppression of antitumor immunity.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 159, No. 5, pp. 609-611, May, 2015
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Ostapchuk, E.O., Perfi l’eva, Y.V., Talaeva, S.Z. et al. Content of HLA-G+ T Cells in the Peripheral Blood from Healthy Women and Breast Cancer Patients. Bull Exp Biol Med 159, 649–651 (2015). https://doi.org/10.1007/s10517-015-3038-y
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DOI: https://doi.org/10.1007/s10517-015-3038-y