Injection of blood serum from mice with Ehrlich’s carcinoma stimulates the growth of transplanted tumor, which proves the presence of tumor-specific factors in the serum. Experiments on (CBA×C57Bl/6)F1 male mice with transplanted Ehrlich’s carcinoma demonstrated the appearance of new proteins in the serum, some of them are identified. The authors suggest continuing the search for tumor-associated factor by combining proteomic analytical methods and testing of identified candidate proteins for their effects on tumor growth.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 10, pp. 491-494, October, 2014
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Kormosh, N.G., Ziganshin, R.K., Shender, V.O. et al. Changes in the Serum Protein Composition in Mice with Transplanted Ehrlich’s Carcinoma. Bull Exp Biol Med 158, 489–492 (2015). https://doi.org/10.1007/s10517-015-2791-2
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DOI: https://doi.org/10.1007/s10517-015-2791-2