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Effects of Permafrost Microorganisms on Skin Wound Reparation

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Local application of ointment with Bacillus spp. strain MG8 (15,000-20,000 living bacterial cells), isolated from permafrost specimens, on the skin wound of about 60 mm2 stimulated the reparation processes in experimental mice. A possible mechanism stimulating the regeneration of the damaged tissues under the effect of MG8 could be modulation of the immune system reactivity with more rapid switchover to humoral immunity anti-inflammatory mechanisms aimed at de novo synthesis of protein.

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Authors and Affiliations

  1. Tyumen’ Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia

    L. F. Kalenova, M. A. Novikova & A. M. Subbotin

Authors
  1. L. F. Kalenova
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  2. M. A. Novikova
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  3. A. M. Subbotin
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Correspondence to L. F. Kalenova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 10, pp. 480-484, October, 2014

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Kalenova, L.F., Novikova, M.A. & Subbotin, A.M. Effects of Permafrost Microorganisms on Skin Wound Reparation. Bull Exp Biol Med 158, 478–482 (2015). https://doi.org/10.1007/s10517-015-2789-9

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  • DOI: https://doi.org/10.1007/s10517-015-2789-9

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