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Photodynamic Inactivation of Bacteria In Vitro Under the Effect of Blue Light

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We studied the photodynamic inactivation of E. coli, S. aureus, and P. aeruginosa in vitro. Bacteria suspensions were incubated with riboflavin and exposed to blue light emitted by a diode matrix. Exogenous photosensitizer riboflavin efficiently inactivated bacteria, while methylene blue was ineffective. Under the effect of blue light in a dose of 117 J/cm2, photoinactivation of E. coli, S. aureus, and P. aeruginosa occurred without photosensitizer riboflavin.

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Authors and Affiliations

  1. Moscow Research Institute of Pediatrics and Pediatric Surgery, Ministry of the Health of the Russian Federation, Moscow, Russia

    E. S. Keshishyan, Z. V. Zaporozhtseva, O. M. Zenina & V. S. Zrodnikov

Authors
  1. E. S. Keshishyan
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  2. Z. V. Zaporozhtseva
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  3. O. M. Zenina
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  4. V. S. Zrodnikov
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Corresponding author

Correspondence to E. S. Keshishyan.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 10, pp. 476-479, October, 2014

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Keshishyan, E.S., Zaporozhtseva, Z.V., Zenina, O.M. et al. Photodynamic Inactivation of Bacteria In Vitro Under the Effect of Blue Light. Bull Exp Biol Med 158, 475–477 (2015). https://doi.org/10.1007/s10517-015-2788-x

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  • DOI: https://doi.org/10.1007/s10517-015-2788-x

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