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Markers of Myocardial Damage in Children of the First Year of Life with Congenital Heart Disease in the Early Period after Surgery with Cardioplegic Anoxia

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We measured the level of cardiac markers (high-sensitivity troponin T and MB fraction of creatine kinase) in children of the first year of life with congenital heart disease in the perioperative period. After cardiac surgery, plasma levels of the above markers exceed the reference limits in the examined children. The diagnosis of myocardial ischemia using biochemical markers in the postoperative period is possible only by dynamic monitoring of the cardiac marker level. The preoperative concentration of high-sensitivity troponin T in children of the first year of life with congenital heart disease can be regarded as a predictor of postoperative complications.

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References

  1. O. A. Kislenko, N. P. Kotlukova, and N. A. Rybalko, Pediatriya. Zh. im. G. I. Speranskogo, 90, No. 5, 6-11 (2011).

    Google Scholar 

  2. Yu. A. Morozov, M. A. Charnaya, I. I. Dement’eva, et al., Kardiol. Serd. Sosud. Khir., 4, No. 5, 63-66 (2011).

    Google Scholar 

  3. M. G. Plyushch, A. A. Kupryashov, C. Yu. Prasolov, et al., Klin. Fiziol. Krovoobr., No. 3, 62-65 (2010).

  4. D. B. Saprykin, Lab. Med., No. 10, 35-38 (2009).

  5. V. I. Shilko, N. V. Galysheva, and E. V. Nikolina, Ross. Vestn. Perinatol. Pediatr., No. 2, 13-17 (2009).

  6. R. H. Christenson, S. H. Duh, F. S. Apple, et al., Clin. Chem., 47, No. 3, 431-437 (2001).

    CAS  PubMed  Google Scholar 

  7. S. J. Clark, P. Newland, C. W. Yoxall, and N. V. Subhedar, Eur. J. Pediatr., 165, No. 2, 87-93 (2006).

    Article  CAS  PubMed  Google Scholar 

  8. Q. Jakobsen, T. Naesheim, K. N. Aas, et al., J. Thorac. Cardiovasc. Surg., 145, No. 3, 812-818 (2013).

    Article  CAS  PubMed  Google Scholar 

  9. M. M. Maddali, J. Valliattu, T. al Delamie, et al., Asian Cardiovasc. Thorac. Ann., 16, No. 4, 274-277 (2008).

    Article  PubMed  Google Scholar 

  10. A. S. McLean and S. J. Huang, Ann. Intensive Care, 2, doi: 10.1186/2110-5820-2-8 (2012).

  11. M. Muller-Bardorff, K. Hallermayer, A. Schröder, et al., Clin. Chem., 43, No. 3, 458-466 (1997).

    CAS  PubMed  Google Scholar 

  12. M. Sugimoto, K. Ota, A. Kajihama, et al., Circ. J., 75, No. 9, 2213-2219 (2011).

    Article  CAS  PubMed  Google Scholar 

  13. A. Tarkowska and W. Furmaga-Jablonska, Scientific World Journal, 2012, doi: 10.1100/2012/682538 (2012).

  14. K. Thygesen, J. S. Alpert, A. S. Jaffe, et al., Circulation, 126, No. 16, 2020-2035 (2012).

    Article  PubMed  Google Scholar 

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Correspondence to E. F. Kozar.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 10, pp. 417-420, October, 2014

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Kozar, E.F., Plyushch, M.G., Popov, A.E. et al. Markers of Myocardial Damage in Children of the First Year of Life with Congenital Heart Disease in the Early Period after Surgery with Cardioplegic Anoxia. Bull Exp Biol Med 158, 421–424 (2015). https://doi.org/10.1007/s10517-015-2776-1

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  • DOI: https://doi.org/10.1007/s10517-015-2776-1

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