Skip to main content
Log in

A New Method for Screening Diagnosis of Insulin Resistance

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

A simple method for the diagnosis of insulin resistance, easily realized in clinical practice, is developed in order to detect patients at a high risk of diseases associated with this condition. The metabolic index is estimated as the proportion of triglycerides and glucose values to quadratic HDL cholesterol value (in mmol/liter). The specifi c feature of this method for detection of insulin resistance in comparison with the known indirect methods is the use of routine biochemical values, evaluated in venous serum, for estimations. Estimation of this metabolic index is an economic and effective indirect method for evaluating the homeostasis system without additional evaluation of blood hormones.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. E. K. Alisheva, E. I. Krasilnikova, and E. V. Shlyakhto, Arterial. Gipertenz., 8, No. 1, 29-34 (2002).

    Google Scholar 

  2. The Metabolic Syndrome [in Russian], Ed. G. E. Roitberg, Moscow (2007).

  3. G. E. Roitberg, T. I. Ushakova, Zh. V. Dorosh, et al., Patent RF No. 2493566. A Method for Screening Diagnosis of Insulin Resistance, Bull. No. 26, September 20, 2013.

  4. N. V. Perova, V. A. Metelskaya, and R. G. Oganov, Kardiologiya, No. 3, 4-9 (2001).

  5. G. E. Roitberg, T. I. Ushakova, and Zh. V. Dorosh, Kardiologiya, 44, No. 3, 94-101 (2004).

    CAS  PubMed  Google Scholar 

  6. G. E. Roitberg, T. I. Ushakova, O. O. Sharkhun, and Zh. V. Dorosh, Kardiologiya, 52, No. 10, 45-50 (2012).

    CAS  PubMed  Google Scholar 

  7. K. G. Alberti and P. Z. Zimmet, Diabet. Med., 15, No. 7, 539-553 (1998).

    Article  CAS  PubMed  Google Scholar 

  8. R. N. Bergman, D. T. Finegood, and M. Ader, Endocr. Rev., 6, No. 1, 45-86 (1985).

    Article  CAS  PubMed  Google Scholar 

  9. E. Borona, P. Moghetti, C. Zancanaro, et al., J. Clin. Endocrinol. Metab., 68, No. 2, 374-378 (1989).

    Article  Google Scholar 

  10. A. Mari, Am. J. Physiol., 272, No. 5, Pt. 1, E925-E934 (1997).

  11. D. R. Matthews, J. P. Hosker, A. S. Rudenski, et al., Diabetologia, 28, No. 7, 412-419 (1985).

    Article  CAS  PubMed  Google Scholar 

  12. T. McLaughlin, G. Reaven, F. Abbasi, et al., Am. J. Cardiol., 96, No. 3, 399-404 (2005).

    Article  CAS  PubMed  Google Scholar 

  13. G. M. Reaven, Diabetes, 37, No. 12, 1595-1607 (1988).

    Article  CAS  PubMed  Google Scholar 

  14. A. J. Scheen, N. Paquot, M. J. Castillo, and P. J. Lefébvre, Diabetes Metab. Rev., 10, No. 2, 151-188 (1994).

    Article  CAS  PubMed  Google Scholar 

  15. D. Tripathy, M. Carlsson, P. Almgren, et al., Diabetes, 49, No. 6, 975-980 (2000).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zh. V. Dorosh.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 9, pp. 389-392, September, 2014

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Roitberg, G.E., Dorosh, Z.V. & Sharkhun, O.O. A New Method for Screening Diagnosis of Insulin Resistance. Bull Exp Biol Med 158, 397–400 (2015). https://doi.org/10.1007/s10517-015-2771-6

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-015-2771-6

Key Words

Navigation