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Morphological and Functional Changes in the Thymus and Spleen of Mouse Offspring in the Development of Systemic Inflammatory Response After a Single Immunity Stimulation in Early Pregnancy

  • MORPHOLOGY AND PATHOMORPHOLOGY
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Bulletin of Experimental Biology and Medicine Aims and scope

We studied morphological and functional changes in the thymus and spleen of mouse offspring subjected to single immune stimulation with concanavalin A at early pregnancy terms against the background of systemic inflammatory response. The offspring was characterized less pronounced accidental involution of the thymus, reduced counts of neutrophils in the marginal zone and red pulp of the spleen, mast cell degranulation, and their reduced content in the red pulp.

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Authors and Affiliations

  1. Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia

    S. S. Obernikhin & N. V. Yaglova

Authors
  1. S. S. Obernikhin
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  2. N. V. Yaglova
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Correspondence to S. S. Obernikhin.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 6, pp. 786-790, June, 2014

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Obernikhin, S.S., Yaglova, N.V. Morphological and Functional Changes in the Thymus and Spleen of Mouse Offspring in the Development of Systemic Inflammatory Response After a Single Immunity Stimulation in Early Pregnancy. Bull Exp Biol Med 157, 812–815 (2014). https://doi.org/10.1007/s10517-014-2673-z

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  • DOI: https://doi.org/10.1007/s10517-014-2673-z

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