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Possible Mechanism of Generation of Nitrite and Non-Thiolate Nitroso Compounds in Blood Plasma during Inflammatory Processes

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Bulletin of Experimental Biology and Medicine Aims and scope

Generation of nitrite (NO2¯) and non-thiolate nitroso compounds in human blood during leukocyte activation mainly occurred due to destruction of NO donors in the plasma, but not due to intensifi cation of NO synthesis. We proposed a mechanism of production of nitrite and non-thiolate nitroso compounds in the blood during infl ammation.

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Authors and Affiliations

  1. N. I. Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, Moscow, Russia

    V. Yu. Titov, V. S. Boldyrikhin, A. V. Ivanova & A. N. Osipov

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  1. V. Yu. Titov
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  2. V. S. Boldyrikhin
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  3. A. V. Ivanova
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  4. A. N. Osipov
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Correspondence to V. Yu. Titov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 4, pp. 479-482, April, 2014

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Titov, V.Y., Boldyrikhin, V.S., Ivanova, A.V. et al. Possible Mechanism of Generation of Nitrite and Non-Thiolate Nitroso Compounds in Blood Plasma during Inflammatory Processes. Bull Exp Biol Med 157, 479–482 (2014). https://doi.org/10.1007/s10517-014-2596-8

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  • DOI: https://doi.org/10.1007/s10517-014-2596-8

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