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Morphofunctional Characteristics of the Glutathione Cycle in Peripheral Blood Erythrocytes of Pregnant Women with a History of Cytomegalovirus Infection Exacerbation during Gestation

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Bulletin of Experimental Biology and Medicine Aims and scope

We studied factors infl uencing peripheral blood erythrocytes of pregnant women with exacerbation of cytomegalovirus infection during gestation. Cytomegalovirus infection was associated with a decrease in the content of reduced glutathione in erythrocytes and glutathione peroxidase, which leads to H2O2 accumulation in the blood. Exacerbation of cytomegalovirus infection was associated with reduction of glutathione reductase and SOD activities. Erythrocyte antioxidant function and the peripheral blood discocyte count decreased. Accumulation of degenerative erythrocytes is fraught with the risk of anemia in pregnant women.

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Authors and Affiliations

  1. Far-Eastern Research Center of Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences, Blagoveshchensk, Russia

    M. T. Lutsenko, I. A. Andrievskaya & O. L. Kutepova

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  1. M. T. Lutsenko
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  2. I. A. Andrievskaya
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  3. O. L. Kutepova
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Correspondence to M. T. Lutsenko.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 2, pp. 246-250, February, 2014

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Lutsenko, M.T., Andrievskaya, I.A. & Kutepova, O.L. Morphofunctional Characteristics of the Glutathione Cycle in Peripheral Blood Erythrocytes of Pregnant Women with a History of Cytomegalovirus Infection Exacerbation during Gestation. Bull Exp Biol Med 157, 278–281 (2014). https://doi.org/10.1007/s10517-014-2544-7

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  • DOI: https://doi.org/10.1007/s10517-014-2544-7

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