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Specific Features of Analgesic Effect of Docosahexaenoic Acid in Rats with Neuropathic Pain Syndrome

  • EXPERIMENTAL BIOLOGY
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Bulletin of Experimental Biology and Medicine Aims and scope

An Erratum to this article was published on 01 April 2014

Experiments on white rats showed that sciatic nerve ligation induced the development of neuropathic pain syndrome: thermal pain threshold decreased, significant reduction in weight bearing of the injured limb, and degenerative changes in the foot tissues. Administration of docosahexaenoic acid reduces activity and duration neuropathic pain syndrome, promoted reversion of weight bearing asymmetry, and prevented the development of degenerative changes in the foot tissues.

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Authors and Affiliations

  1. A. V. Zhirmunskii Institute of Marine Biology, Far Eastern Division of Russian Academy of Sciences, Vladivostok, Russia

    I. V. Dyuizen, I. V. Manzhulo, O. S. Ogurtsova, N. E. Lamash, N. A. Latyshev & S. V. Kas’yanov

  2. School of Biomedicine, Vladivostok State Medical University, Vladivostok, Russia

    I. V. Manzhulo

Authors
  1. I. V. Dyuizen
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  2. I. V. Manzhulo
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  3. O. S. Ogurtsova
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  4. N. E. Lamash
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  5. N. A. Latyshev
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  6. S. V. Kas’yanov
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Correspondence to I. V. Manzhulo.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 156, No. 11, pp. 647-649, November, 2013

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Dyuizen, I.V., Manzhulo, I.V., Ogurtsova, O.S. et al. Specific Features of Analgesic Effect of Docosahexaenoic Acid in Rats with Neuropathic Pain Syndrome. Bull Exp Biol Med 156, 699–701 (2014). https://doi.org/10.1007/s10517-014-2428-x

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  • DOI: https://doi.org/10.1007/s10517-014-2428-x

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