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Effects of Composition of Biocomposite Materials Implanted into Hole Defects of the Metaphysis on the Reparative Regeneration and Mineralization of Bone Tissue

Bulletin of Experimental Biology and Medicine volume 156, pages 285–289 (2013)Cite this article

We carried out a comparative analysis of morphological pattern and element composition of regenerated bone tissue forming in the metaphysis defects after substitution of these defects with calcium phosphate substance containing low-molecular non-collagen bone proteins with various affinities to ion exchangers. We have found that regenerated tissue in the defects grew from the edges to the center and its element composition depended on the maturity of newly formed bone tissue. Implantation material containing non-collagen bone proteins with various affinities to ion exchangers induced no significant changes in the content of analyzed elements of bone tissue around the defect. The content of analyzed elements in the areas distant from the defect area did not change during the experiment.

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Affiliations

  1. Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics, Ministry of Health and Social Development of the Russian Federation, Kurgan, Russia

    S. N. Luneva, I. A. Talashova, E. V. Osipova, A. N. Nakoskin & A. A. Emanov

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  1. S. N. Luneva
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  2. I. A. Talashova
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  3. E. V. Osipova
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  4. A. N. Nakoskin
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  5. A. A. Emanov
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Corresponding author

Correspondence to E. V. Osipova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 156, No. 8, pp. 255-259, August, 2013

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Luneva, S.N., Talashova, I.A., Osipova, E.V. et al. Effects of Composition of Biocomposite Materials Implanted into Hole Defects of the Metaphysis on the Reparative Regeneration and Mineralization of Bone Tissue. Bull Exp Biol Med 156, 285–289 (2013). https://doi.org/10.1007/s10517-013-2331-x

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  • DOI: https://doi.org/10.1007/s10517-013-2331-x

Key Words

  • hole defects
  • calcium phosphate substance
  • element composition of bone tissue
  • reparative regeneration