The existence of lipid-radical cycles in membranes as an LPO alternative has been proven. Cytochrome b5 seems to play the key role in the formation of these cycles. The functional role of lipid-radical cycles in cell metabolism, including the positive effect on microsomal and mitochondrial oxidation, is discussed.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 156, No. 8, pp. 156-160, August, 2013
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Agadzhanyan, Z.S., Doroshchuk, A.D., Shiryaeva, Y.K. et al. Role of Cytochrome b5 and α-Tocopherol to Microsomal and Mitochondrial Oxidation. Bull Exp Biol Med 156, 191–195 (2013). https://doi.org/10.1007/s10517-013-2308-9
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DOI: https://doi.org/10.1007/s10517-013-2308-9