We studied the cardioprotective properties of mexidol and 3-hydroxypyridine fumarate in rat model of chronic myocardial injury. We found that 3-hydroxypyridine fumarate (25 mg/kg) produced more pronounced antioxidant and cardioprotective effects than mexidol (25 mg/kg).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 155, No. 2, pp. 176-178, February, 2013
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Zamotaeva, M.N., Chairkin, I.N., Inchina, V.I. et al. Experimental Substantiation for the Use of Mexidol and 3-Hydroxypyridine Fumarate in Chronic Myocardial Injury. Bull Exp Biol Med 155, 212–213 (2013). https://doi.org/10.1007/s10517-013-2115-3
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DOI: https://doi.org/10.1007/s10517-013-2115-3