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Age-Related Differences in Rat Multipotent Mesenchymal Stromal Bone Marrow Cells

Bulletin of Experimental Biology and Medicine volume 155, pages 129–133 (2013)Cite this article

We studied multipotent mesenchymal stromal cells isolated from the bone marrow of young (1 month) and old (>12 months) rats. The cell cultures derived from old rats were characterized by lower cell yield in the primary culture, lower number of doublings, and reduced colony-forming capacity of precursor cells.

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Affiliations

  1. Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia

    M. P. Valyushina & L. B. Buravkova

Authors
  1. M. P. Valyushina
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  2. L. B. Buravkova
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Corresponding author

Correspondence to L. B. Buravkova.

Additional information

Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 1, pp. 11-15, January, 2013

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Valyushina, M.P., Buravkova, L.B. Age-Related Differences in Rat Multipotent Mesenchymal Stromal Bone Marrow Cells. Bull Exp Biol Med 155, 129–133 (2013). https://doi.org/10.1007/s10517-013-2097-1

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  • DOI: https://doi.org/10.1007/s10517-013-2097-1

Key Words

  • aging
  • multipotent mesenchymal stromal cells
  • colony-forming units
  • proliferation