Morphofunctional pecularities of the bone marrow neutrophil maturation were studied in the progeny of female rats with chronic experimental toxic hepatitis, similar to hepatitis B by morphological, biochemical, and physiological characteristics. The lysosomal, phagocytic, and killing activities of cells were reduced during the morphologically identifi able stages of neutrophilopoiesis (myeloblasts, promyelocytes, myelocytes, metamyelocytes, stab and segmented neutrophils).
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G. V. Bryukhin and E. V. Vtorushina, Morfologich. Vedomosti, Nos. 3-4, 16-18 (2006).
G. V. Bryukhin, G. I. Mikhailova, and E. N. Pashnina, Morfologiya, No. 3, 48-51 (2005).
G. V. Bryukhin and A. A. Fedosov, Vestn. Chelyabinsk. Gos. Ped. Univer., No. 6, 157-158 (2006).
A. I. Vengerovskii and A. S. Saratikov, Farmakol. Toksikol., 51, No. 1, 89-92 (1988).
I. I. Dolgushin, Yu. S. Andreeva, and A. Yu. Savochkina, Neutrophilic Extracellular Traps and Methods for Evaluating the Neutrophil Function [in Russian], Moscow (2009).
Immunological, Cytochemical, and Biochemical Methods for Studies of Phagocytic Cells. Methodological Recommendations, Ed. E. A. Imelbaeva [in Russian], Ufa (1996).
D. V. Mazurov, K. F. Khamidullina, and B. V. Pinegin, Immunology, No. 1, 57-61 (2000).
A. N. Mayansky and O. I. Pikuza, Clinical Aspects of Phagocytosis [in Russian], Kazan (1993).
O. Yu. Rebrova, Statistical Analysis of Medical Data. Use of STATISTICA Software [in Russian], Moscow (2002).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 155, No. 1, pp. 114-117, January, 2013
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Bryukhin, G.V., Nevzorova, N.V. Contribution of Maternal Chronic Experimental Hepatic Disease to the Development of Nonspecific Cell Resistance in the Progeny. Bull Exp Biol Med 155, 104–107 (2013). https://doi.org/10.1007/s10517-013-2091-7
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DOI: https://doi.org/10.1007/s10517-013-2091-7