Experimental models of stomatitis developing in response to an isolated (radiation) and combined (radiation and chemical) exposure of experimental animals, were created. The severity of radiation-induced stomatitis was determined by the dose of radiation exposure. Additional exposure to a chemical factor (cyclophosphamide) augmented the destructive effect of ionizing radiation on the buccal mucosa of rats.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 12, pp. 785-788, December, 2012
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Antushevich, A.A., Grebenyuk, A.N., Antushevich, A.Y. et al. Experimental Simulation of Radio- and Chemoradio Stomatitis in Rats. Bull Exp Biol Med 154, 814–817 (2013). https://doi.org/10.1007/s10517-013-2063-y
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DOI: https://doi.org/10.1007/s10517-013-2063-y