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Anticoagulant Effects of Arginine-Containing Peptide Arg-Pro-Gly-Pro under Conditions of Immobilization Stress

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Bulletin of Experimental Biology and Medicine Aims and scope

Anticoagulant, fibrinolytic, and antiplatelet effects of RPGP peptide were found in animals under stress conditions caused by single or repeated immobilization. The observed properties of the peptide extend the study of agents protecting the organism under conditions of hypercoagulation occurring under stress conditions and help to re-evaluate the role of glyprolines as contributors to the maintenance of adaptation capacities in various pathologies.

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Authors and Affiliations

  1. Laboratory of Blood Protective Systems, Biological Faculty, M. V. Lomonosov State Moscow University, Moscow, Russia

    M. E. Grigorjeva, M. Kh. Kazancheva & L. A. Lyapina

Authors
  1. M. E. Grigorjeva
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  2. M. Kh. Kazancheva
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  3. L. A. Lyapina
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Correspondence to M. E. Grigorjeva.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 12, pp. 687–691, December, 2012

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Grigorjeva, M.E., Kazancheva, M.K. & Lyapina, L.A. Anticoagulant Effects of Arginine-Containing Peptide Arg-Pro-Gly-Pro under Conditions of Immobilization Stress. Bull Exp Biol Med 154, 723–727 (2013). https://doi.org/10.1007/s10517-013-2039-y

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  • DOI: https://doi.org/10.1007/s10517-013-2039-y

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