We studied morphological and cell characteristics of stenosis of esophagogastric and esophagocolonic anastomosis. It was demonstrated that sclerogenesis in the gastric transplants is associated with hypertrophy of leiomyocytes, hyperelastosis foci, degenerative and atrophic modifi cations of the glands, and foveolar cell hypersecretion. In colonic transplant, collagen synthesis predominates in the esophageal anastomosis and can be associated with proliferation of blood capillaries; hyperplastic reactions of leiomyocytes and elastic fi bers are minor, colonocytes exhibit high secretory activity. Differences in the cell reactions of the transplants reflect complex character of the formation of esophageal anastomosis stenosis.
Similar content being viewed by others
References
G. A. Lapii, L. M. Nepomnyashchikh, Yu. V. Chikinev, and A. V. Kutepov, Pathomorphology of Artificial Esophagus in Gastric Tube plasty [in Russian], Moscow (2012).
D. S. Murashko and V. M. Durleshter, Fundamental. Issled., No. 1, 140-147 (2011).
L. M. Nepomnyashchikh, G. A. Lapii, Yu. V. Chikinev, et al., Byull. Eksp. Biol. Med., 153, No. 2, 238–243 (2012).
A. F. Chernousov, D. V. Ruchkin, F. A. Chernousov, and D. A. Balalykin, Diseases of Artificial Esophagus [in Russian], Moscow (2008).
A. F. Chernousov, D. V. Ruchkin, and A. V. Tavadov, Khirurgia, No. 12, 60–64 (2008).
J. W. Briel, A. P. Tamhankar, J. A. Hagen, et al., J. Am. Coll. Surg., 198, No. 4, 536–541 (2004).
S. Cherki, J. Y. Mabrut, M. Adham, et al., Ann. Chir., 130, No. 4, 242-248 (2005).
C. F. Estofolete, C. Botelho-Machado, S. R. Taboga, et al., Cancer Cell Int., No. 10, 18 (2010).
E. Gounot, J. Borgnon, F. Huet, and E. Sapin, J. Pediatr. Surg., 41, No. 3, 592–595 (2006).
L. Kotsis, Z. Krisar, K. Orban, and A. Csekeo, Eur. J. Cardiothorac. Surg., 21, No. 1, 79-83 (2002).
T. W. Rice, Thorac. Surg. Clin., 16, No. 1, 63-73 (2006).
M. Van Heijl, J. A. Gooszen, P. Fockens, et al., Ann. Surg., 251, No. 6, 1064-1069 (2010).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nepomnyashchikh, L.M., Lapii, G.A., Chikinev, Y.V. et al. Cell Reactions in Gastric Tube and Colon Transplants in Stenoses of Esophageal Anastomosis. Bull Exp Biol Med 154, 574–580 (2013). https://doi.org/10.1007/s10517-013-2002-y
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-013-2002-y