Ependymal cells of cerebral ventricles are the most probable candidate progenitor cells. We studied ependymal and subventricular zone cells expressing intermediate filament protein vimentin. The results suggest that the ventricular ependyma represent a homogenous cell population. Some ependymocytes have long processes contacting with blood vessels, which makes them similar to tanycytes of the third cerebral ventricle. New data on the structure of ependymocyte processes attest to their active involvement into creation of a special microenvironment for neural stem cells of the subventricular proliferative zone.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. V. Gilyarov, Morfologiya, 131, No. 1, 85–90 (2007).
O. V. Kirik, O. S. Alekseeva, and D. E. Korzhevskii, Morfologiya, 139, No. 2, 77–79 (2011).
D. E. Korzhevskii, Med. Akad. Zh., 10, No. 10, 175–182 (2010).
D. E. Korzhevskii, I. P. Grigor’ev, and V. A. Otelin, Morfologiya, 129, No. 1, 85–86 (2006).
D. E. Korzhevskii, O. V. Kirik, and A. V. Gilyarov, Morfologiya, 140, No. 6, 86–88 (2011).
D. E. Korzhevskii, O. V. Kirik, M. N. Karpenko, et al., Theoretical Bases and Practical Application of Immunohistochemical Methods [in Russian], St. Petersburg (2012).
D. E. Korzhevskii, O. V. Kirik, E. G. Sukhorukova, and T. D. Vlasov, Morfologiya, 141, No. 2, 28–32 (2012).
D. E. Korzhevskii, E. G. Sukhorukova, O. V. Kirik, and O. S. Alekseeva, Morfologiya, 140, No. 3, 77–79 (2011).
V. A. Otellin and D. E. Korzhevskii, Morfologiya, 122, No. 6, 14–18 (2002).
G. T. Sukhikh and V. V. Malaitsev, Byull. Eksper. Biol., 131, No. 3, 244–255 (2001).
K. N. Yarygin and V. N. Yarygin, Zh. Nevrol. Psikhiatr., 112, No. 1, 4–14 (2012).
A. Alvarez-Buylla, M. Kohwi, T. M. Nguyen, and F. T. Merkle, Cold Spring Harb. Symp. Quant. Biol., 73, 357–365 (2008).
M. Bolborea, M. P. Laran-Chich, K. Rasri, et al., Endocrinology, 152, No. 10, 3871–3883 (2011).
M. Carlen, K. Meletis, C. Goritz, et al., Nat. Neurosci., 12, No. 3, 259–267 (2009).
A. I. Danilov, Z. Kokaia, and O. Lindvall, Neuroscience, 214, 159–170 (2012).
A. V. Gilarov, D. E. Korzhevskii, and V. A. Otellin, J. Evol. Biochem. Physiol., 45, No. 1, 147–155 (2009).
C. B. Johansson, S. Momma, D. L. Clarke, et al., Cell, 96, No. 1, 25–34 (1999).
D. E. Korzhevskii, M. V. Lentsman, O. V. Kirik, and V. A. Otellin, Neurosci. Behav. Physiol., 38, No. 8, 845–848 (2008).
F. D. Miller and A. Gauthier-Fisher, Cell Stem Cell, 4, No. 6, 507–510 (2009).
S. Uchida, T. Imagawa, M. Furue, et al., J. Vet. Med. Sci., 73, No. 3, 319–323 (2011).
T. Voight, J. Comp. Neurol., 289, No. 1, 74–88 (1989).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 4, pp. 210–214, October, 2012
Rights and permissions
About this article
Cite this article
Kirik, O.V., Korzhevskii, D.E. Vimentin in Ependymal and Subventricular Proliferative Zone Cells of Rat Telencephalon. Bull Exp Biol Med 154, 553–557 (2013). https://doi.org/10.1007/s10517-013-1998-3
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-013-1998-3