Bulletin of Experimental Biology and Medicine

, Volume 154, Issue 2, pp 186–188 | Cite as

Possible Neurophysiological Markers of Early Neurodegenerative Process: Parkinson’s Disease

  • B. Kh. BaziyanEmail author

We used tests for evaluation of latent period, duration, and accuracy of eyes, head, or hand movements and their coordinated movements. Comparative analysis of these parameters was performed in healthy subjects and in patients with early stages of Parkinson’s disease. The pathology data significantly (p<0.05) differed from those in normal control subjects. These results can be used as neurophysiological markers of early neurodegenerative process. Increasing the number of tests would lead to better specificity of the markers. It will be possible to create a battery of neurophysiological tests most likely reflecting the predictive basis of early neurodegenerative process.

Key Words

Parkinson’s disease eye, head, and hand movements coordination neurophysiological markers neurodegenerative processes 


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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  1. 1.Laboratory of Neurocybernetics, Research Center of NeurologyRussian Academy of Medical SciencesMoscowRussia

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