Possible Neurophysiological Markers of Early Neurodegenerative Process: Parkinson’s Disease
- 132 Downloads
We used tests for evaluation of latent period, duration, and accuracy of eyes, head, or hand movements and their coordinated movements. Comparative analysis of these parameters was performed in healthy subjects and in patients with early stages of Parkinson’s disease. The pathology data significantly (p<0.05) differed from those in normal control subjects. These results can be used as neurophysiological markers of early neurodegenerative process. Increasing the number of tests would lead to better specificity of the markers. It will be possible to create a battery of neurophysiological tests most likely reflecting the predictive basis of early neurodegenerative process.
Key WordsParkinson’s disease eye, head, and hand movements coordination neurophysiological markers neurodegenerative processes
Unable to display preview. Download preview PDF.
- 1.B. Kh. Baziyan and I. E. Dmitriyev, Zh. Vyssh. Nervn. Deyat, 46, No. 2, 396–399 (1996).Google Scholar
- 3.B. Kh. Baziyan, A. Ju. Shvetsov, E. A. Ivanova, and G. A. Yakovlev, in: Structural-Functional and Neurochemical Patterns of Brain Asymmetry and Plasticity [in Russian], Moscow (2007), pp. 62–66.Google Scholar
- 4.Diseases of the Nervous System: a Guide for Physicians, Eds. N. N. Yachno and D. R. Shtulman [in Russian], Moscow (2001).Google Scholar
- 5.S. N. Illarioshkin, T. B. Zagorovskaya, I. A. Ivanova-Smolenskaya, and E. D. Markova, Nevrol. Zh., No. 5, 47–52 (2002).Google Scholar
- 6.S. N. Illarioshkin, S. A. Klyushnikov, L. V. Brylev, et al., Nevrol. Zhurn., No. 5, 47–54 (2006).Google Scholar
- 7.A. I. Kubarko, M. L. Kolesnikova, and N. P. Kubarko, Zdravookhraneniye, No. 1, 18–22 (2003).Google Scholar