We studied the effect of liposome preparation containing taxifolin oligomers and taxifolin conjugates with carbonyl compounds on skin regeneration after chemical burn. The preparations containing fl avonoid conjugates intensifi ed regeneration processes and reparation of hair follicles and sebaceous glands after chemical burn. The preparation based on taxifolin conjugate with acetaldehyde was most effective; its activity was comparable with that of the wound-healing preparation Olasol. Taxifolin conjugates with carbonyl compounds can be used for the creation of combined wound- and burn-healing preparations.
Similar content being viewed by others
References
A. A. Naumov, Yu. V. Shatalin, and M. M. Potselueva, Byull. Eksp. Biol., 149, No. 1, 69-73 (2010).
A. A. Naumov, Yu. V. Shatalin, T. K. Sukhomlin, et al., Klet. Tekhnol. Biol. Med., No. 2, 96-102 (2009).
Yu. V. Shatalin, Complexes of Flavonoids with Metals of Alternating Valence [in Russian], Pushchino (2010).
Yu. V. Shatalin and A. N. Shmarev, Biofi zika, 55, No. 1, 75-82 (2010).
V. S. Shubina and Yu. V. Shatalin, Thitologiya, 54, No. 3, 251-260 (2012).
N. E. Es-Safi , V. Cheynier, and M. Moutounet, J. Agric. Food Chem., 50, No. 20, 5571-5585 (2002).
L. C. Huber, J. H. Distler, F. Moritz, et al., Arthritis Rheum., 56, No. 8, 2755-2764 (2007).
F. Ishii, A. Takamura, and Y. Ishigami, Langmuir, 11, No. 2, 483-486 (1995).
H. Wang, X. Liu, T. Umino, et al., Am. J. Respir. Cell Mol. Biol.,. 25, No. 6, 772-779 (2001).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 3, pp. 160-166, July, 2012
Rights and permissions
About this article
Cite this article
Shubina, V.S., Shatalin, Y.V. Skin Regeneration after Chemical Burn under the Effect of Taxifolin-Based Preparations. Bull Exp Biol Med 154, 152–157 (2012). https://doi.org/10.1007/s10517-012-1897-z
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-012-1897-z