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Immunohistochemical Detection of Two Neuronal Populations Involved in Two Different Episodes of Animal Cognitive Activity

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We developed a method to detect and superimpose neuronal populations involved in two different episodes of activity in the brain of single animal. This method is based on usage of two transcriptional factors with different accumulation curves, c-Fos and pCREB, as the markers. The overlap of neuronal populations involved in performance of spatial and nonspatial tasks in Morris water maze has been shown to occur at “chance” level.

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Authors and Affiliations

  1. Laboratory of Neurobiology of Memory, P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia

    S. A. Chekhov, D. V. Bezriadnov, O. I. Ivashkina, E. M. Amelchenko & K. V. Anokhin

  2. National Research Center “Kurchatov Institute”, Moscow, Russia

    S. A. Chekhov, D. V. Bezriadnov, O. I. Ivashkina, E. M. Amelchenko & K. V. Anokhin

Authors
  1. S. A. Chekhov
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  2. D. V. Bezriadnov
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  3. O. I. Ivashkina
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  4. E. M. Amelchenko
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  5. K. V. Anokhin
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Corresponding author

Correspondence to S. A. Chekhov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 7, pp. 130-132, July, 2012

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Chekhov, S.A., Bezriadnov, D.V., Ivashkina, O.I. et al. Immunohistochemical Detection of Two Neuronal Populations Involved in Two Different Episodes of Animal Cognitive Activity. Bull Exp Biol Med 154, 115–117 (2012). https://doi.org/10.1007/s10517-012-1889-z

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  • DOI: https://doi.org/10.1007/s10517-012-1889-z

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