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Contribution of the Complement System to Realization of Biological Fluid Cytotoxicity in Health and Disease

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Bulletin of Experimental Biology and Medicine Aims and scope

The cytotoxic effects of human blood serum were studied under normal and pathological conditions. The contribution of the complement system to the realization of this effect was demonstrated. Signifi cant differences in the serum capacity to kill foreign cells were detected for healthy subjects and asthmatics. Bovine sperm suspension can serve as the test object for rapid evaluation of functional activity of the complement system.

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Authors and Affiliations

  1. Institute of Pathology and Pathophysiology, the Russian Academy of Medical Sciences, Moscow, Russia

    E. N. Arkhipova, Yu. S. Medvedeva, I. B. Alchinova & M. Yu. Karganov

  2. P. K. Anokhin Institute of Physiology, the Russian Academy of Medical Sciences, Moscow, Russia

    A. B. Cherepov

Authors
  1. E. N. Arkhipova
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  2. A. B. Cherepov
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  3. Yu. S. Medvedeva
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  4. I. B. Alchinova
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  5. M. Yu. Karganov
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Corresponding author

Correspondence to E. N. Arkhipova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 5, pp. 611-614, May, 2012

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Arkhipova, E.N., Cherepov, A.B., Medvedeva, Y.S. et al. Contribution of the Complement System to Realization of Biological Fluid Cytotoxicity in Health and Disease. Bull Exp Biol Med 153, 658–660 (2012). https://doi.org/10.1007/s10517-012-1791-8

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  • DOI: https://doi.org/10.1007/s10517-012-1791-8

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