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Free and Protein-Bound Angiotensin II1-7 in the Regulation of Drinking Behavior and Hemodynamics in Rats

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Bulletin of Experimental Biology and Medicine Aims and scope

We compared physiological activity of synthetic analogues of endogenous protein-peptide compounds, complexes of angiotensin II1-7 with functionally different proteins (transport protein, serum albumin; and neurospecifi c Ca2+-binding protein, S100b). Physiological activity of angiotensin II1-7 was shown to depend on the type of a carrier protein. Our results suggest that complexes of angiotensins with BSA and S100b are strong factors for the integration of central and peripheral functions at the homeostatic and behavioral level.

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References

  1. A. V. Kotov, S. M. Tolpygo, E. I. Pevtsova, and M. F. Obukhova, Ros. Fiziol. Zh., 88, No. 6, 686-698 (2002).

    CAS  Google Scholar 

  2. E. I. Pevtsova, S. M. Tolpygo, M. F. Obukhova, and A. V. Kotov, Byull. Eksp. Biol. Med., 146, No. 8, 135-137 (2008).

    Google Scholar 

  3. E. I. Pevtsova, S. M. Tolpygo, M. F. Obukhova, and A. V. Kotov, Byull. Eksp. Biol. Med., 147, No. 11, 491-495 (2009).

    Google Scholar 

  4. S. M. Tolpygo, Vestn. NovGU. Ser. Med. Nauki, No. 35, 82-85 (2006).

  5. S. M. Tolpygo, E. I. Pevtsova, A. V. Kotov, and K. V. Sudakov, Zh. Vyssh. Nervn. Deyat., 47, No. 6, 955-963 (1997).

    CAS  Google Scholar 

  6. C. N. Bradford, D. R. Ely, and M. K. Raizada, Curr. Hypertens. Rep., 12, No. 4, 212-219 (2010).

    Article  PubMed  CAS  Google Scholar 

  7. A. N. Cat and R. M. Touyz, Peptides, 32, No. 10, 2141-2150 (2011).

    Article  Google Scholar 

  8. D. Daniels, D. K. Yee, L. F. Faulconbridge, and S. J. Fluharty, Endocrinology, 146, No. 12, 5552-5560 (2005).

    Article  PubMed  CAS  Google Scholar 

  9. T. Y. M. Gwathmey, K. D. Pendergrass, S. D. Reid, et al., Hypertension, 55, No. 1, 166-171 (2010).

    Article  PubMed  CAS  Google Scholar 

  10. L. Hunyady and K. J. Catt, Mol. Endocrinol., 20, No. 5, 953-970 (2006).

    Article  PubMed  CAS  Google Scholar 

  11. D. Iusuf, R. H. Henning, W. H. van Gilst, and A. J. M. Roks, Eur. J. Pharmacol., 585, Nos. 2-3, 303-312 (2008).

    Article  PubMed  CAS  Google Scholar 

  12. M. Kurdi, W. C. De Mello, and G. W. Booz, Int. J. Biochem. Cell Biol., 37, No. 7, 1357-1367 (2005).

    Article  PubMed  CAS  Google Scholar 

  13. R. A. Santos, A. J. Ferreira, E. Simoes, and A. C. Silva, Exp. Physiol., 93, No. 5, 519-527 (2008).

    Article  PubMed  CAS  Google Scholar 

  14. J. W. Wright and J. W. Harding, Progr. Neurobiol., 95, No. 7, 49-67 (2011).

    Article  CAS  Google Scholar 

  15. J. W. Wright, B. J. Yamamoto, and J. W. Harding, Ibid., 84, No. 2, 157-181 (2008).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Laboratory for Physiology of Motivations, P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia

    S. M. Tolpygo, E. I. Pevtsova, B. B. Shoibonov & A. V. Kotov

Authors
  1. S. M. Tolpygo
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  2. E. I. Pevtsova
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  3. B. B. Shoibonov
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  4. A. V. Kotov
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Corresponding author

Correspondence to S. M. Tolpygo.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 5, pp. 573-576, May, 2012

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Tolpygo, S.M., Pevtsova, E.I., Shoibonov, B.B. et al. Free and Protein-Bound Angiotensin II1-7 in the Regulation of Drinking Behavior and Hemodynamics in Rats. Bull Exp Biol Med 153, 623–626 (2012). https://doi.org/10.1007/s10517-012-1782-9

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  • DOI: https://doi.org/10.1007/s10517-012-1782-9

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