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Excretion of Himantane and Its Metabolites with the Urine and Feces in Rats

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Bulletin of Experimental Biology and Medicine Aims and scope

The levels of himantane and its metabolites in daily urine and feces of rats were measured after intraperitoneal and oral dose of 25 mg/kg. The injected dose of the initial substance and 1.3% its metabolites were eliminated with excrements within 24 h after administration via both routes 0.23%.

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Authors and Affiliations

  1. Laboratory of Pharmacokinetics, V. V. Zakusov Institute of Pharmacology, the Russian Academy of Medical Sciences, Moscow, Russia

    E. A. Litvin, D. V. Bastrygin, G. B. Kolyvanov, K. V. Alekseyev & V. P. Zherdev

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  1. E. A. Litvin
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  2. D. V. Bastrygin
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  3. G. B. Kolyvanov
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  4. K. V. Alekseyev
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  5. V. P. Zherdev
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Correspondence to E. A. Litvin.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 4, pp. 470-472, April, 2012

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Litvin, E.A., Bastrygin, D.V., Kolyvanov, G.B. et al. Excretion of Himantane and Its Metabolites with the Urine and Feces in Rats. Bull Exp Biol Med 153, 481–482 (2012). https://doi.org/10.1007/s10517-012-1746-0

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  • DOI: https://doi.org/10.1007/s10517-012-1746-0

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