Dexamethasone increased the levels of active caspase-3 form in the brain cortex of neonatal rats 120 h after drug administration, but did not affect the expression of this key apoptotic protease in the brain 6 or 24 h postinjection. Increased expression of the active form of caspase-3 in the cerebral cortex was associated with earlier eye opening and delayed formation of startle-reflex in rats.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 4, pp. 467-469, April, 2012
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Menshanov, P.N., Muzyka, V.V. & Dygalo, N.N. Effects of Dexamethasone on the Development of Neonatal Rats and Level of Active Caspase-3 in Brain Cortex. Bull Exp Biol Med 153, 478–480 (2012). https://doi.org/10.1007/s10517-012-1745-1
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DOI: https://doi.org/10.1007/s10517-012-1745-1